Myriam Borzee/iStockBy MORGAN WINSOR, ABC News(NEW YORK) — A pandemic of the novel coronavirus has now killed more than 1.3 million people worldwide.Over 57.4 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks. The criteria for diagnosis — through clinical means or a lab test — has also varied from country to country.The United States is the worst-affected nation, with more than 11.9 million diagnosed cases and at least 254,383 deaths.Nearly 200 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.Here’s how the news is developing Monday. All times Eastern:Nov 23, 7:09 amRussia reports over 25,000 new cases for first timeRussia confirmed 25,173 new cases of COVID-19 and an additional 361 fatalities from the disease in the last 24 hours, according to the country’s coronavirus response headquarters.It’s the first time that Russia has reported over 25,000 newly diagnosed infections in a single day, setting a new record for the country. The cumulative total now stands at 2,114,502 confirmed cases, including 36,540 deaths, according to the coronavirus response headquarters.Despite the growing number of infections and deaths, Russian authorities have repeatedly said they have no plans to impose another nationwide lockdown. Kremlin spokesman Dmitry Peskov told reporters Monday that it’s up to regional authorities to decide what measures need to be imposed in their regions to curb the spread of the virus.The Eastern European nation of 145 million people has the fifth-highest tally of COVID-19 cases in the world, behind only the United States, India, Brazil and France, according to a real-time count kept by Johns Hopkins University.Nov 23, 5:39 amUS reports over 142,000 new casesThere were 142,732 new cases of COVID-19 confirmed in the United States on Sunday, according to a real-time count kept by Johns Hopkins University.It’s the 20th straight day that the country has reported over 100,000 newly diagnosed infections. Sunday’s count falls under the all-time high of 196,004 new cases on Nov. 20.An additional 921 fatalities from COVID-19 were also registered nationwide on Sunday, down from a peak of 2,609 new deaths on April 15.A total of 12,247,487 people in the United States have been diagnosed with COVID-19 since the pandemic began, and at least 256,783 of them have died, according to Johns Hopkins. The cases include people from all 50 U.S. states, Washington, D.C. and other U.S. territories as well as repatriated citizens.Much of the country was under lockdown by the end of March as the first wave of the pandemic hit. By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country’s cases then hovered around 20,000 for a couple of weeks before shooting back up and crossing 100,000 for the first time on Nov. 4.Nov 23, 4:41 amAstraZeneca, Oxford say their vaccine is up to 90% effectiveU.K.-based pharmaceutical giant AstraZeneca and England’s University of Oxford announced Monday that late-stage trials show their COVID-19 vaccine was up to 90% effective in preventing the disease.The results are based on interim analysis of phase 3 trials in the United Kingdom and Brazil, which looked at two different dosing regimens. One regimen showed vaccine efficacy of 90% when the drug, called AZD1222, was given as a half dose, followed by a full dose at least one month apart. A second regimen showed 62% efficacy when given as two full doses at least one month apart. The combined analysis from both dosing regimens showed an average efficacy of 70%, according to press releases from AstraZeneca and Oxford.There were a total of 131 COVID-19 cases in the analysis, and no hospitalizations or severe cases of the disease were reported in participants receiving the vaccine candidate, according to the press releases.“These findings show that we have an effective vaccine that will save many lives,” Andrew Pollard, director of the Oxford Vaccine Group and chief investigator of the Oxford vaccine trial, said in a statement Monday. “Excitingly, we’ve found that one of our dosing regimens may be around 90% effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply.”AstraZeneca, which has promised not to profit from the vaccine “for the duration of the pandemic,” said it will now immediately prepare to submit the data to regulators around the world — including in the United Kingdom, Europe and Brazil — that have framework in place for conditional or early approval. The company will also seek an emergency use listing from the World Health Organization for an accelerated pathway to vaccine availability in low-income nations.Meanwhile, Oxford said it is submitting the full analysis of the interim results for independent scientific peer review and publication.“Today marks an important milestone in our fight against the pandemic,” AstraZeneca CEO Pascal Soriot said in a statement Monday. “This vaccine’s efficacy and safety confirm that it will be highly effective against COVID-19 and will have an immediate impact on this public health emergency. Furthermore, the vaccine’s simple supply chain and our no-profit pledge and commitment to broad, equitable and timely access means it will be affordable and globally available, supplying hundreds of millions of doses on approval.”The U.K. government has already placed orders for 100 million doses of the AstraZeneca/Oxford vaccine candidate, along with 40 million doses of another developed by Pfizer and BioNTech which has shown to have 95% efficacy.Copyright © 2020, ABC Audio. All rights reserved.
Three MERS cases confirmed in Qatar’s capitalQatar has reported three more MERS cases to the World Health Organization (WHO), the WHO said yesterday. The three cases are related, and all case-patients are from Doha.The first case-patient is a 67-year-old woman who developed symptoms of Middle East respiratory syndrome coronavirus (MERS-CoV) infection at the end of November, and died on Dec 12. The source of her illness is still under investigation.”The patient had neither a history of contact with dromedary camels nor recent travel. Follow up and screening of seven household contacts and 40 healthcare worker contacts is ongoing and two asymptomatic secondary cases have been identified so far,” the WHO said.The woman’s son, age 50, and a 32-year-old case contact have also been diagnosed as having MERS-CoV. Both patients were asymptomatic and identified during contact tracing. The WHO said a total of 47 identified contacts of the patient have been monitored daily for the appearance of respiratory or gastrointestinal symptoms for a period of 2 weeks following their last exposure to the patient.From 2012 through Nov 30, 2019, a total of 2,494 laboratory-confirmed MERS-CoV cases and 858 associated deaths have been reported to the WHO, the vast majority in Saudi Arabia.Dec 26 WHO report Six countries report more polio cases; WHO extends polio emergencyIn the latest global polio developments, Afghanistan and Pakistan reported more wild poliovirus type 1 (WPV1) cases, and four African nations reported more circulating vaccine-derived poliovirus type 2 (cVDPV2) cases, according to totals reflected on the Global Polio Eradication Initiative (GPEI) tables, which include data reported as of Dec 24.The GPEI didn’t publish its full report with paralysis onsets, noting that the weekly updates will resume on Jan 9.ProMED Mail, the online reporting system of the International Society for Infectious Diseases (ISID) compiled a report on the recent cases compared to the previous weekly polio totals. It said for WPV1 cases, Afghanistan has two more, one each from Fara and Kandahar provinces, raising its total for the year to 26. Pakistan has 10 more cases from Balochistan, Khyber-Pakhtunkhwa, Punjab, Sindh, and Islamabad provinces, pushing its number for 2019 to 111.Meanwhile, four African countries reported five new cVDPV2 cases, including two from Angola and one each from Central African Republic, Chad, and Ethiopia.GPEI WPV1 cases as of Dec 24 GPEI vaccine-derived polio cases as of Dec 24 Dec 26 ProMED Mail postIn other polio developments, the World Health Organization’s (WHO) polio emergency committee met for the 23rd time on Dec 11, and after hearing from experts and representatives from polio-affected countries unanimously agreed that the risk of international spread remains a public health emergency of international concern (PHEIC).The WHO said in a Dec 20 statement on the deliberations that the committee voiced grave concerns about the significant rise in WPV1 cases this year, along with widespread transmission, vaccine refusal, and detection of vaccine-derived cases in Pakistan and challenging security and inaccessibility problems in Afghanistan.Regarding vaccine-derived polio, the group said multiple outbreaks in four of the WHO regions are very concerning, noting that since its last meeting, seven new countries have reported outbreaks. WHO emergency committees typically meet every 3 months or sooner if needed.Dec 20 WHO statement WHO details yellow fever outbreak in MaliThe WHO yesterday released more details about a yellow fever outbreak in Mali that has so far resulted in three confirmed cases, plus nine suspected and three probable infections.The initial case-patient is a 15-year-old girl from Koulikoro region who had not traveled outside of her district and had not been vaccinated. The other confirmed infections are in two men ages 17 and 25 from Ivory Coast who are living in Bouguimi district in Mali’s Sikasso region. Two of the people with confirmed infections died.The suspected and probable cases are all from Bouguimi district, and there are three deaths among the suspected infections.The WHO said mass yellow fever campaigns have been underway in Mali since 2008, but coverage is still below herd immunity thresholds and there are pockets of low immunity, with high population movements within and outside of the country possibly diluting population immunity.The district where the first patient is from is near Bamako, Mali’s capital and home to 2 million people. The district where the two other patients lived is near the Ivory Coast border. The WHO said the risk of yellow fever spread within Mali due to disease activity is high, the risk of regional spread is moderate, and the threat of global spread is low.Dec 26 WHO statement Dec 9 CIDRAP news scan “Health officials confirm 3 yellow fever cases in Mali, Ivory Coast”
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Indian Oil Corporation informed an interim sales purchase agreement was signed with Mitsubishi Corporation for supply of 0.7 MMTPA of LNG for 20 years from the Cameron LNG project in the USA.The company’s LNG sales registered a growth of 6.3% in the financial year 2014-2015 reaching 3.42 million metric tons, IOC’s Chairman B. Ashok said at a press conference.He said that in order to secure LNG supplies, the corporation has forayed into independent LNG purchase besides tying up for 1.2 MMTPA of LNG for 20 years with Pacific North West LNG Project, Canada.Deliveries from the Pacific NorthWest LNG project are expected to commence in 2020 while deliveries from the Cameron LNG project should begin two years earlier, in the first quarter of 2018, the company informed.The volumes will be delivered to IOC’s planned LNG import terminal at Kamarajar Port in Ennore. LNG World News Staff; Image: Cameron LNG
IN FIVE EASY PIECES WITH TAKE 5 Sydney Olympic silver medalist Eric Wainaina will compete in the April 20 Nagano Marathon, race organizers said Friday.The Japan-based Kenyan, bronze medalist in the 1996 Atlanta Olympic marathon and runnerup to Ethiopia’s Gezahgne Abera in Sydney four years later, was originally set to run in the Boston Marathon on April 21 but decided instead to take part in the race over the Nagano Olympic Memorial Course. GET THE BEST OF THE JAPAN TIMES
Embed from Getty ImagesBoss Antonio Conte says goalkeeper Thibaut Courtois will be fit for Chelsea’s Champions League game against Atletico Madrid on Wednesday despite needing treatment after a nasty fall during the 4-0 win over Stoke.Courtois came to claim a corner but collided with Gary Cahill when in mid air and landed awkwardly.AdChoices广告But the Belgian did not suffer concussion and was able to carry on.Conte was about to bring on Cesc Fabregas at the time and waited for confirmation Courtois was OK before making the change.“I spoke with the doctor and I asked if Thibaut was OK and the answer was positive. He said you can make another substitution,” the Italian explained.“The player is OK to play the next game at Atletico Madrid.” See also:Morata scores hat-trick as Chelsea thrash StokeHughes insists Alonso should have been sent offAlonso substitution was tactical, says ConteFive Chelsea players in England’s Under-17 World Cup squadConte: It’s the right moment for HazardStoke v Chelsea player ratingsCosta completes move back to Atletico Follow West London Sport on TwitterFind us on Facebook