Amazon CEO Jeff Bezos and the Matrix Global Logistics Park in Staten Island (Google Maps; Getty)Amazon’s industrial footprint in New York City is officially Bigfoot-sized.The e-commerce giant secured a 975,000-square-foot warehouse at the Matrix Global Logistics Park in Staten Island, Crain’s reported. It was the largest industrial deal of the past quarter, according to a CBRE report that did not identify the tenant.Amazon has already leased two other warehouses on the site near Goethals Bridge, bringing its capacity there to nearly 2.3 million square feet. Ikea is also a tenant at the complex, having leased a 975,000-square-foot warehouse.Since losing its proposed HQ2 in Long Island City in 2019, Amazon has been on a tear through New York City’s property market. On the office side, the company leased 335,000 square feet of office space from SL Green near Hudson Yards and bought the Lord & Taylor building on Fifth Avenue from WeWork for $1 billion.It’s also picked up a significant amount of industrial space, leasing a Bronx warehouse spanning more than 200,000 square feet last year. It also reportedly signed a lease on RXR Realty’s massive vertical warehouse in Maspeth.Leasing activity in the industrial sector has seen an uptick in demand as home-bound shoppers make more of their purchases online, according to CBRE. E-commerce companies have dominated new leases signed in that sector.Industrial tenants inked deals for 1.6 million square feet of space in the five boroughs during the third quarter of the year, a nearly 71 percent increase over the same time last year, according to CBRE. [Crain’s] — Orion Jones TagsamazonCommercial Real EstateIndustrial Real EstateStaten Island Share on FacebookShare on TwitterShare on LinkedinShare via Email Share via Shortlink Share via Shortlink
Metro News:Just 60 seconds of adrenaline-pumping activity can ‘seriously damage’ their recollection of the event, according to UK scientists.They say forgetfulness is often triggered by high-energy events like chasing a suspect.Lorraine Hope, from the University of Portsmouth, believes her findings, published in journal Psychological Science, flag up the potential problems with witness statements.She said: ‘Police officers are often expected to remember in detail who said what and how many blows were received or given in the midst of physical struggle or shortly afterwards.‘The results of our tests indicate it may be very difficult for them to do this.’Dr Hope added: ‘As exhaustion takes over, cognitive resources tend to diminish. The ability to fully shift attention is inhibited, so even potentially relevant information might not be processed.’Read the whole story: Metro News
Microcephaly screening for Zika complications in newborns might miss some birth defects, according to a long-awaited analysis of the first 1,500 suspected cases in Brazil, which revealed instances of brain damage in babies with normal head circumference, a team from Brazil reported yesterday.In the largest case series to date, published in The Lancet, researchers from Brazil said screening criteria should be adjusted to include signs and symptoms of brain abnormalities.In a related research development, pathology examination of postmortem samples from infants and fetuses from Brazil at US Centers for Disease Control and Prevention (CDC) labs revealed Zika antigens, cell damage, but no sign of Zika outside of the central nervous system and no indication that other pathogens are involved.Defects in babies with normal head sizeIn the surveillance study, the researchers analyzed investigations completed as of Feb 27 by medical teams of 1,501 live-born babies with suspected microcephaly.Using clinical data from Brazil’s Ministry of Health, they grouped the cases into five categories based on neuroimaging and Zika virus lab findings. Categories ranged from definite microcephaly to discarded. The team also looked at head circumference, first-week mortality, and history of maternal rash.Of the total, 899 cases were discarded. Among the remaining 602, 76 were definite, 54 highly probable, 181 moderately probable, and 291 somewhat probable. Compared with the discarded cases, definite or probable ones had small head circumference, and mothers were more likely to have had a rash during pregnancy (21% vs 61%). Infants in the definite and probable groups were also four time more likely to die during the first week of life.The analysis also revealed brain abnormalities in babies with normal head size who were born to mothers who had a Zika-like rash in late pregnancy. The investigators noted that cranium development is generally complete by week 30 of gestation, so infants can be born with normal head size and still have brain damage. They also said the findings raise the possibility that Zika infection in newborns might lead to brain damage.Cesar Victora, MD, PhD, the study’s lead author, said in a Lancet press release, “Although we believe that the underreporting of microcephaly cases is rare during the epidemic, newborns infected with the virus late in pregnancy may go unreported due to their head size being within normal range.” He also noted that about a third of the mothers of babies in the definite and probable group reported no rash during pregnancy.Examination of all newborns during epidemic waves should be considered, Victora said, and he warned that because southern Brazil experienced a wave of Zika in early 2016, the country could see a second spike in microcephaly at the end of the year.In a related commentary in the same Lancet issue, two experts from Brazil said adding new neurologic symptom criteria to detect Zika cases would be useful for identifying all affected infants, but many medical settings don’t have the specialized personnel. The authors are Jorg Heukelbach, MD, MPH, PhD, a community health specialist from the School of Medicine at Federal University of Ceara, and Guilherme Loureiro Werneck, MD, PhD, with the epidemiology department at the State University of Rio de Janeiro.Another option would be incorporating an accurate serologic test into routine prenatal care, and they said validation of such a test should be a research priority.Damage in postmortem and placental samplesIn the pathology study, also published yesterday in The Lancet, researchers from the CDC and collaborators in Brazil analyzed tissue from three babies born with microcephaly who died and two placentas from mothers who miscarried at 11 and 13 weeks’ gestation. In all five instances, the mothers reported Zika symptoms during their first pregnancy trimesters.In the three fatal cases, investigators found Zika antigens in neurons and glial cells. Brain tissue analysis showed cell damage, calcium deposits, and death. Unlike for other infections such as herpes, they found no sign of substantial inflammatory response or specific structural effects.No evidence of Zika virus were found in other organ systems, and the three babies showed a range of birth defects and brain abnormalities.In placental samples from the two miscarriages, investigators found Zika virus antigens. For all five cases, tests ruled out other infectious causes.The authors said the mechanism that causes the birth defects still isn’t clear, but it is probably related to the virus attacking the nervous system, resulting in brain damage and muscle impairment.In an accompanying commentary, two US-based experts said though the CDC has concluded that Zika virus causes microcephaly, detections of Zika virus in tissues are scarce. The authors are Drucilla Roberts, MD, a pathologist at Massachusetts General Hospital (MGH), and Matthew Frosch, MD, PhD, a neuropathologist at MGH and Harvard University.They said more detailed pathology studies are needed to identify the full spectrum of Zika virus infection and to confirm the link to perinatal complications. Roberts and Frosch also recommended that future studies should include histopathologic examination of tissue at different gestational ages.”This report highlights that we can learn much about the pathogenesis of Zika virus congenital infection through careful pathological investigation, but leaves us with many questions for study,” the two wrote.Other developmentsThe CDC today reported 4 more Zika-related birth defects in US pregnant women, raising the total to 12 as of Jun 23. Three of the new cases involved live births, and one involved a pregnancy loss. The number of Zika-related birth defects in the US territories remained the same, at one. In other numbers updates, the CDC reported 22 more Zika infections in US pregnant women (raising the total to 287), and 34 more in pregnant women in the US territories (raising the total to 250). Regarding infections in the general population, the CDC reported 166 more cases in US territories where the virus is spreading locally, most of them in Puerto Rico. The total in the region stands at 2,020 now, and 3 more Guillain-Barre syndrome cases were reported, boosting the total to 10. US states reported 115 more Zika illnesses in travelers, increasing the total to 934, plus 2 more sexually transmitted Zika cases, putting that number at 13.Though most Americans have heard of Zika virus, only 13% are aware of the impact on adults and only half know that the virus can spread sexually, the Kaiser Family Foundation reported today in a health tracking poll for June. The poll also found widespread support for Zika funding, including assistance with reproductive services for women in outbreak areas in and outside of the United States.The CDC on Jun 28 added Anguilla to its level 2 travel notice for Zika virus. There are now 49 countries or territories listed among the CDC’s Zika travel advisories.See also:Jun 29 Lancet report on Zika microcephaly surveillanceJun 29 Lancet related commentaryJun 29 related Lancet press releaseJun 29 Lancet report on Zika birth defect pathologyJun 29 Lancet related commentaryJun 29 related Lancet press release
PITTSBURGH (AP) — BeeJay Anya watched his teammates put up all the shots they wanted for more than 39 minutes. Then the burly forward made the only two that mattered in the final 45 seconds.Anya’s tip-in got North Carolina State within a point of LSU and his left-handed hook just before the buzzer lifted the eight-seeded Wolfpack to a 66-65 victory in the NCAA Tournament on Thursday night.The final play was designed for teammate Trevor Lacey, but LSU bottled up the senior guard, and the ball ended up in Anya’s willing hands.“I was like know what, it’s time for me to shoot the ball,” Anya said. “Trevor called for it back. He had a chance. It was my turn to shoot it.”Just as importantly, it was his time to make it. Next up for the Wolfpack (21-13) is top-seeded Villanova on Saturday thanks to Anya’s deft touch and a maddening collapse by the Tigers.LSU (22-11) led by 16 early in the second half but missed its last 12 field goals and six crucial free throws in the final minutes.“We wasn’t ready for our season to end right now,” LSU sophomore forward Jarell Martin said. “We worked real hard and felt like we had a great shot.”Just not the last one, even if it wasn’t quite the way coach Mark Gottfried drew it up.“Beejay just made an instinctive play,” Gottfried said.Cat Barber led N.C. State with 17 points and Abdul-Malik Abu added 13 as the Wolfpack provided another jolt during a typically frantic opening day of the tournament. N.C. State’s win was the fifth one-point game of the day, a record.“Amazing things can happen,” Gottfried said. “Today was a great day, exciting day in that regard. For us, being a part of it, being on the good end, it ended up being a great day for us too.”Tim Quarterman led LSU with 17 points. Martin had 16 points and 11 rebounds, and Jordan Mickey had 12 points and 14 boards for the Tigers, who appeared to be in firm control before the latest and most painful collapse during an otherwise promising season.A week after falling to Auburn in the Southeastern Conference tournament, the Tigers’ breakout season under third-year coach Johnny Jones ended with a thud.“We weren’t able to convert on the offensive end,” Martin said. “We did a great job of moving the ball around from side to side, but we just couldn’t get the ball to fall in.”Jones admitted he wasn’t sure how his young team would react while making the program’s first NCAA appearance in six years, maybe because the Tigers have been a talented but uneven work in progress all winter.LSU alleviated any of Jones’ concerns early. Riding the athleticism of their two sophomore big men and Quarterman’s budding confidence, the Tigers attacked. LSU filled the lane repeatedly, soaring over the Wolfpack at times and racing around them at others.During one sequence in the first half, Martin banked in a running layup, and then followed with a putback dunk in which his right hand appeared to be even with the square on the backboard before he grabbed the ball and slammed it through.Mickey ended the half with a traditional three-point play, and then a dunk as the Tigers took a seemingly commanding 40-26 lead.Like just about everything else this year for the Tigers, comfort was fleeting.MURKY FUTUREThe future might be bright in Baton Rouge, but it’s not exactly clear. Martin and Mickey were first-team All-SEC selections. Now they head back to campus weighing whether to return for one more run or test the professional waters.I’ll get with coach Jones, my parents and we’ll come to a conclusion,” Martin said. “I don’t have a time period on it.”TIP INSLSU: The Tigers finished 12 of 22 at the free-throw line and shot just 29 percent (7 of 24) in the second half. … LSU outscored 28 points in the paint alone in the first half, more than N.C. State managed during the opening 20 minutes.N.C. State: The Wolfpack made just 5 of 24 3-pointers. … Lacey had nine points and nine rebounds in 38 minutes. … Former LSU player Ralston Turner had 10 points against his former team.UP NEXTLSU’s season is over.N.C. State plays Villanova on Saturday.
COLUMBIA, S.C. (AP) — Stanley “Boom” Williams ran for 107 yards on 14 carries as Kentucky held on to beat South Carolina 26-22 on Saturday night.The Wildcats (2-0, 1-0 Southeastern) snapped a 22-game road losing streak despite gaining 92 yards and getting just four first downs in the second half.South Carolina (1-1, 0-1) had a chance to tie on a two-point conversion midway through the fourth quarter, but Pharoh Cooper fumbled on the try and Denzil Ware returned the ball 98 yards to give Kentucky two points and what proved to be the final margin.Cooper had nine catches for 100 yards. Junior quarterback Perry Orth took over for injured starter Connor Mitch. He was 13-of-20 for 179 yards, but threw an interception with 4:32 to go at the Wildcats 26 with the Gamecocks down four.It was Kentucky’s first SEC road win in six years.___AP college football website: collegefootball.ap.org